研究実績

1.原著論文(査読つき)

48) K. Matsuyama, T. Inoue, T. Muroga, N. Arima, M. Doe, F. Tani, Y. Ookawa, Y. Okamoto, S. Onitsuka, H. Okamura, T. Iwagawa, T. Hamada. New halogenated C15 acetogenins from Okinawan sea hare Aplysia dactylomela, 2022年, Tetrahedron, 132889.

47) S-Y Ng, C-S Phan, T. Ishii, T. Kamada, T. Hamada, C. S. Vairappan. Terpenoids from Marine Soft Coral of the Genus Xenia in 1977 to 2019,2020年,molecules,25巻 5386,DOI: 10.3390/molecules25225386 

46) T. Hamada, K. Kobayashi, N. Arima, F. Tani, C. S. Vairappan, S. Onitsuka, H. Okamura. Two cytotoxic squalene-derived polyethers from the Japanese red alga Chondria armata,2020年,Natural Product Research,DOI: 10.1080/14786419.2020.1777411.

45) T. Hamada, K. Harano, R. Niihara, H. Kitahara, M. Yamamoto, C. S. Vairrapan, F. Tani, S. Onitsuka and H. Okamura. Composition and monthly changes of the volatile constituents in the sour Hetsuka-daidai citrus peel,2020年,Journal of Oleo Science,69巻 6号,643-648ページ

44) T. Kawahata, K. Kawahara, M. Shimokawa, A. Sakiyama, T. Shiraishi, K. Minami, M. Yamamoto, Y. Shinsato, K. Arima, T. Hamada, and T. Furukawa. Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5-FU,2020年,ONCOLOGY LETTERS,19巻,2258-2264ページ

43) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada, C. S. Vairrapan. 12-Epi-9-deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral, Xenia sp.,2019年,Natural Product Research,33巻 3号,808-813ページ

42) T. Hamada, Y. Matsumoto, C.-S. Phan, T. Kamada, S. Onitsuka, H. Okamura, T. Iwagawa, N. Arima, F. Tani and C. S. Vairappan. Aaptamine-related Alkaloid from the Marine Sponge Aaptos aaptos.,2019年,Natural Product Communications,14巻 9号,1-3ページ

41) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada and C. S. Vairappan. Cytotoxic Sesquiterpenoids From Soft Soral Capnella imbricate.,2019年,Natural Product Communications,14巻 6号,1-4ページ

40) S. Onitsuka, T. Hamada, H. Okamura. Preparation of antimicrobial gold and silver nanoparticles from tea leaf extracts.,2019年,Colloids and Surfaces B: Biointerfaces,173巻,242-248ページ

39) C.-S. Phan, T. Kamada, T. Hamada, C. S. Vairappan. Cytotoxic Sesterterpenoids from Bornean Sponge Spongia sp.,2018年,Rec. Nat. Prod.,12巻 6号,頁 643-647ページ

38) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada, C. S. Vairappan. A new guaiane-type sesquiterpenoid from a bornean soft coral, Xenia stellifera,2018年,Natural Product Communications,13巻 1号,15-16ページ

37) T. Kamada, C.-S. Phan, T. Hamada, K. Hatai, C. S. Vairappan. Cytotoxic and antifungal terpenoids from bornean soft coral, Sinularia flexibilis,2018年,Natural Product Communications,13巻 1号,17-19ページ

36) C.-S. Phan, T. Kamada, K. Kobayashi, T. Hamada, C. S. Vairappan.15-deoxy-isoxeniolide-A, new diterpenoid from a bornean soft coral, Xenia sp.,2018年,Natural Product Research,32巻 2号,202-207ページ

35) K. Maeda, T. Hamada, S. Onitsuka, H. Okamura. Total Synthesis of the Claimed Structure of (±)-Hyptinin and Structural Revision of Natural Hyptinin,2017年,Journal of Natural Products,80巻 5号,1446-1449ページ

34) M. I. Mohie, Y. Takenoshita, T. Hamada, S. Onitsuka, J. Kurawaki, and H. Okamura. Spontaneous Preparation of Highly Stable Gold Nanoparticle Stabilized with ω-Sulfonylated alkylsulfanylaniline,2017年,Journal of Oleo Science,66巻 12号,1349-1354ページ

33) T. Hamada, M. Hayasaki, H. Kitahara, K. Yamashita, A. Kariyazaki, S. Onitsuka, H. Okamura. Essential oil composition of citrus peels in Kikai-jima Island, Japan,2017年,American Journal of Essential Oils and Natural Products,5巻,12-15ページ

32) T. Hamada, D. Harada, M. Hirata, K. Yamashita, K. Palaniveloo, H. Okamura, T. Iwagawa, N. Arima, T. Iriguchi, N. J. de Voogd and C. S. Vairappan. Manoalide-related Sesterterpene from the Marine Sponge Luffariella variabilis,2015年,Natural Product Communications,10巻,863-864ページ

31) R. Ohira, T. Hamada, S. Onitsuka, and H. Okamura. Base-catalyzed Asymmetric Diels-Alder Reaction of N-Nosyl-3-hydroxy-2-pyridone with a Chiral Acrylate, and Its Application to the Synthesis of Aminocarbasugars,2015年,Global Science and Technology Forum JChem,2巻,16-20ページ

30) Y. Koyanagi, T. Hamada, T. Iwagawa, and H. Okamura. Asymmetric Synthesis of Ampelomin A and ent-Epiampelomin A, 2015年,Journal of Oleo Science,64巻,449-454ページ

29) T. Hamada, Y. White, M. Nakashima, Y. Oiso, M. Fujita, H. Okamura, T. Iwagawa, N. Arima. The bioassay-guided isolation of growth inhibitors of adult T-cell leukemia (ATL), from the Jamaican plant Hyptis verticillata, and NMR characterization of hyptoside, 2012年,Molecules,17巻,9931-9938ページ

28) 岡村 浩昭, 岩川 哲夫, 濱田 季之. ジエンの活性化を基盤とする触媒的Diels-Alder反応の開発と生理活性シクロヘキセンオキシド類およびカルバ糖類合成への応用, 2012年 ,有機合成化学協会誌,70巻 ,3号 ,227-239ページ

27) H. Okamura, F. Urabe, T. Hamada, and T. Iwagawa. Base-Catalyzed Asymmetric Diels-Alder Reaction of 3-Hydroxy-2-pyrone and Simple Aryl Vinyl Sulfoxide: Asymmetric Synthesis of Carbaketopyranoses, 2012年,Bull. Chem. Soc. Jpn. ,85巻,631-633ページ

26) Y. White, T. Hamada, M. Yoshimitsu, M. Nakashima, M.Hachiman, T. Kozako, K. Matsushita, K. Uozumi, S. Suzuki, H. Kofune, T. Furukawa, N. Arima. Novel cytotoxic isolated from Jamaican Hyptis verticillata jacq induces apoptosis and overcomes multidrug resistance,2011年,Anticancer Research,31巻,4251-4258ページ

25) N. T. Kipassa, H. Okamura, T. Hamada, Y. Morimoto, M. Doe, T. Iwagawa, M. Nakatani. Rings D-seco and B,D-seco tetranortriterpenoids from root bark of Entandrophragma angolense, 2011年,Phytochemistry,72巻,1854-1858ページ

24) T. Iwagawa, T. Kusatsu, K. Tsuha, T. Hamada, H. Okamura, T. Furukawa, S. Akiyama, M. Doe, Y. Morimoto, F. Iwase, K. Takemura. Cytotoxic eunicellin-type diterpenes from the soft coral Liophyton viscudium, 2011年,Heterocycles,83巻, 2149-2155ページ

23) 濱田 季之. 最大の天然物 ポリセオナミドの構造決定, 2011年, 化学と生物, 49巻 11号, 755-761ページ

22) H. Okamura, J. Kurawaki, T. Iwagawa, T. Hamada, M. Kawashima. One-step Preparation of Gold Nanoparticles Using 4-Acylamindothiophenol as a Reductive Stabilizer, 2010年, Chem. Lett., 12巻, 1258-1260ページ

21) T. Hamada, S. Matsunaga, M. Fujiwara, K. Fujita, H. Hirota, R. Schmucki, P. Guentert, N. Fusetani. Solution structure of polytheonamide B, a highly cytotoxic nonribosomal polypeptide from marine sponge, 2010年, J. Am. Chem. Soc., 132巻, 12941 - 12945 ページ

20) M. Hirashima, K. Tsuda, T. Hamada, H. Okamura, T. Furukawa, S. Akiyama, Y. Tajitsu, R. Ikeda, M. Komatsu, M. Doe, Y. Morimoto, M. Shiro, R. W. M. van Soest, K. Takemura, and T. Iwagawa. Cytotoxic isomalabaricane derivatives and a monocyclic triterpene glycoside from the sponge Rhabdastrella globostellata. 2010年, J. Nat. Prod., 73巻, 1512-1518ページ

19) H. Okamura, H. Iiji, T. Hamada, T. Iwagawa, T. Furuno. Diels-Alder reaction of a-tropolone and electron-deficient dienophiles prompted by Et3 or silica gel: a new synthetic method of highly functionalized homobarrelenone derivatives. 2009年, Tetrahedron, 65巻, 10709-10714ページ

18) N. T. Kipassa , H. Okamura, K. Kina, T. Hamada, T. Iwagawa. Efficient short step synthesis of Corey's tamiflu intermediate, 2008年, Organic Lett., 10巻, 815-816ページ

17) T. Ueki, K. Shintaku, Y. Yonekawa, N. Takatsu, H. Yamada, T. Hamada, H. Hiroshi, and H. Michibata Identification of Vanabin-interacting protein 1 (VIP1) from blood cells of the vanadium-rich ascidian Ascidia sydneiensis samea, 2007年, Biochimica et Biophysica Acta - General Subjects, 1770巻, 951-957 ページ

16) K. Takada, T. Hamada, H. Hirota, Y. Nakao, S. Matsunaga, R. W. M. van Soest, and N. Fusetani Asteropine A, a Sialidase-Inhibiting Conotoxin-like Peptide from the Marine Sponge Asteropus simplex, 2006年, Chemistry & Biology, 13巻, 569-574 ページ

15) T. Hamada , Y. Ito, T. Abe, F. Hayashi, P. Guentert, M. Inoue, T. Kigawa, T. Terada, M. Shirouzu, M. Yoshida, A. Tanaka, S. Sugano, S. Yokoyama, and H. Hirota Solution structure of the antifreeze-like domain of human sialic acid synthase, 2006年, Protein Sci., 15巻, 1010-1016 ページ

14) K. Warabi, T. Hamada, Y. Nakao, S. Matsunaga, H. Hirota, R. W. M. van Soest, and N. Fusetani Axinelloside A, an Unprecedented Highly Sulfated Lipopolysaccharide Inhibiting Telomerase, from the Marine Sponge, Axinella infundibula, 2005年, J. Am. Chem. Soc., 127巻, 13262 - 13270 ページ

13) T. Hamada, M. Asanuma, T. Ueki, F. Hayashi, N. Kobayashi, S. Yokoyama, H. Michibata, and H. Hirota Solution Structure of Vanabin2, a Vanadium(IV)-Binding Protein from the Vanadium-Rich Ascidian Ascidia sydneiensis samea, 2005年, J. Am. Chem. Soc., 127巻, 4216 - 4222 ページ

12) T. Hamada, S. Matsunaga, G. Yano, and N. Fusetani Polytheonamides A and B, Highly Cytotoxic Linear Polypeptides of Unprecedented Structural Features, from the Marine Sponge Theonella swinhoei, 2005年, J. Am. Chem. Soc., 127巻, 110 - 118 ページ

11) T. Hamada, H. Hirota, S. Yokoyama, M. Yamaguchi, N. Otsubo, H. Ishida, M. Kiso, A. Kanamori, and R. Kannagi NMR structure elucidation of cyclic sialyl 6-sulfo Lewis x, a biologically dormant form of L-selectin ligand. 2003年, Tetrahedron Lett., 44巻, 1167 - 1170 ページ

10) T. Hamada, H. Hirota, S. Yokoyama, N. Otsubo, H. Ishida, M. Kiso, A. Kanamori, and R. Kannagi NMR analysis of novel ganglioside GM4 analogues containing de-N-acetyl and lactamized sialic acid: probes for searching new ligand structures for human L-selectin, 2002年, Magn. Reson. Chem., 40巻, 517 - 523 ページ

9) S. Tsukamoto, K. Tomise, K. Miyakawa, B-C. Cha, T Abe, T. Hamada, H. Hirota, and T. Ohta CYP3A4 inhibitory activity of new bisalkaloids, dipiperamides D and E, and cognates from white pepper, 2002年, Bioorg. Med. Chem., 10巻, 2981 - 2985 ページ

8) H. Furukawa, T. Hamada, M. K. Hayashi, T. Haga, Y. Muto, H. Hirota, S. Yokoyama, K. Nagasawa, and M. Ishiguro (H. Furukawa and T. Hamada contributed equally to this work.) Conformation of ligands bound to the muscarinic acetylcholine receptor, 2002年, Mol. Pharmacol, 62巻, 778 - 787 ページ

7) H. Furukawa, T. Haga, Y. Muto, S. Yokoyama, T. Hamada, and H. Hirota Conformation of (S)-methacholine bound to the M2 muscarinic acetylcholine receptor, 2001年, Life Sci., 68巻, 22 - 23 ページ

6) T. Hamada, T. Sugawara, S. Matsunaga, and N. Fusetani Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei, 2. Structure Elucidation, 1994年, Tetrahedron Lett., 35巻, 609 - 612 ページ

5) T. Hamada, T. Sugawara, S. Matsunaga, and N. Fusetani Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei, 1. Isolation and Component Amino Acids, 1994年, Tetrahedron Lett., 35巻, 719 - 720 ページ

4) T. Kusumi, T. Hamada, M. Hara, M. O. Ishitsuka, H. Ginda, and H. Kakisawa Structure and Absolute Configuration of Isoclavukerin A, a Component from an Okinawan Soft Coral of Clavularia species, 1992年, Tetrahedron Lett., 33巻, 2019 - 2022 ページ

3) T. Hamada, T. Kusumi, M. O. Ishitsuka, and H. Kakisawa Strucutre and Absolute Configurations of New Lobane Diterpenoids from the Okinawan Soft Coral Sinularia flexibilis, a Marine Diterpene, by a Modified Mosher Method, 1992年, Chem. Lett., 33 - 36 ページ

2) T. Kusumi, T. Hamada, M. O. Ishitsuka, I. Otani, and H. Kakisawa Elucidation of the Relative and Absolute Stereochemistry of Lobatriene, a Marine Diterpene, by a Modified Mosher Method, 1992年, J. Org. Chem., 57巻, 1033 - 1035 ページ

1) T. Iwagawa, T. Hamada, S. Kuroki, and T. Hase Iridoids from Catalpa bignonioides, 1991年, Phytochemistry, 30巻, 4057 - 4060 ページ

2.国際会議発表

21) Toshiyuki Hamada, Kazushi Kobayashi, Naomichi Arima, Fumito Tani, Charles Santhanaraju Vairappan, Yuka Motoi, Satoaki Onitsuka and Hiroaki Okamura“Squalene-derived polyethers, inhibiting Adult T-cell Leukemia cell, isolated from the red alga, Chondria armata.” 第23回国際海藻学会(23rd International Seaweed Symposium)(口頭発表)2019年4月30日、韓国、済州市

20) Kaoru Warabi, Toshiyuki Hamada, Shigeki Matsunaga, Hiroshi Hirota, Rob W. M. van Soest, Nobuhiro Fusetani: Axinelloside A, a telomerase-inhibitory highly sulfated lipopolysaccharide from the marine sponge, Axinella infundibula. The 2005 International Chemical Congress of Pacific Basin Societies・Honoruru, Hawaii, USA・December, 2005. 

19) Yoko Ito, Toshiyuki Hamada, Takamasa Abe, Fumiaki Hayashi, Peter Guntert, Makoto Inoue, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Mayumi Yoshida, Akiko Tanaka, Sumio Sugano, Shigeyuki Yokoyama, Hiroshi Hirota Structural and functional analyses of the antifreeze-like domain of human sialic acid synthase. The 1st Asia-Pacific NMR Symposium・Yokohama, Japan・November, 2005.
18) Toshiyuki Hamada, Miwako Asanuma, Tatsuya Ueki, Fumiaki Hayashi, Naohiro Kobayashi, Shigeyuki Yokoyama, Hitoshi Michibata, Hiroshi Hirota Solution structure of vanadium-binding protein, Vanabin2, from a vanadium-rich ascidian, Ascidia sydneiensis samea, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Hyderabad, India・January, 2005.
17) Toshiyuki Hamada, Miwako Asanuma, Tatsuya Ueki, Hitoshi Michibata, Hiroshi Hirota Solution structure of Vanabin2, a vanadium-binding protein in a vanadium-rich ascidian, Ascidia sydneiensis samea, International Symposium on Marine Natural Products・Sorrento, Italy・September, 2004.
16) Kentaro Takada, Yoichi Nakao, Toshiyuki Hamada, Hiroshi Hirota, Shigeki Matsunaga, Nobuhiro Fusetani Structure of a neuraminidase inhibitor from the marine sponge Asteropus simplex, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003
15) Mizue Yamazaki, Yoshihiro Suzuki, Toshiyuki Hamada, Hiroshi Hirota Chemical cues on metamorphosis in ascidians, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
14) Hiroshi Hirota, Reiko Ban, Toshiyuki Hamada, Seketsu Fukuzawa, Shigeki Matsunaga, Nobuhiro Fusetani Mode of action of onnamide A, a cytotoxic compound from the marine sponge Theonella swinhoei, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
13) Toshiyuki Hamada, Shigeki Matsunaga, Masako Fujiwara, Kenichi Fujita, Hiroshi Hirota, Nobuhiro Fusetani Three dimensional structure of polytheonamide B, a potent cytotoxic polypeptide from the marine sponge Theonella swinhoei, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
12) Toshiyuki Hamada, Hiroshi Hirota, Akiko Kanamori, Reiji Kannagi, Nobumasa Otsubo, Hideharu Ishida, Makoto Kiso, Shigeyuki Yokoyama NMR Analysis of Cyclic Sialyl 6-Sulfo Lewis X; Structure Elucidation and Selectin Binding Activity, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Tronto, Canada・August, 2002.
11) Takamasa Abe, Toshiyuki Hamada, Wataru Kagawa, Hitoshi Kurumizaka, Takehiko Shibata, Shigeyuki Yokoyama, Hiroshi Hirota Conformation Analysis of Single-Stranded DNA Bound to Human Rad52 by TRNOE Experiments, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Tronto, Canada・August, 2002.
10) Takamasa Abe, Toshiyuki Hamada, Wataru Kagawa, Hitoshi Kurumizaka, Takehiko Shibata, Hiroshi Hirota, Shigeyuki Yokoyama Transferred NOE studies of single-starnded DNA bound to the DNA repair protein HsRad52, Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
9) Reiko Ban, Wakana Saikawa, Shinichi Nishimura, Mizue Yamazaki, Wakana Ohashi, Seketsu Fukuzawa, Toshiyuki Hamada, Hiroshi Hirota Toward the discovery of the target proteins of bioactive compounds, Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
8) Toshiyuki Hamada, Hiroshi Hirota, Hiroyasu Furukawa, Yutaka Muto, Shigeyuki Yokoyama, Tatsuya Haga Conformational analysis of ligands bound to the muscarinic acetylcholine receptor by TR-NOE, Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
7) Hiroshi Hirota, Seketsu Fukuzawa, Toshiyuki Hamada, Reiko Ban, Takashi Kunishima, and Chie Kawabata: Research on mode of action of marine natural products I. Chemical modification of bioactive compounds from marine sponges. 10th International Symposium on Marine Natural Products, Okinawa, June, 2001.
6) Toshiyuki Hamada, Seketsu Fukuzawa, Miwako Asanuma, Mizue Yamazaki, Reiko Ban, Shigeyuki Yokoyama, and Hirota Hiroshi: Research on mode of action of marine natural products II. Molecular interaction analysis of bioactive compounds. 10th International Symposium on Marine Natural Products, Okinawa, June, 2001.
5) Toshiyuki Hamada, Hirota Hiroshi, Furukawa hiroyasu, Tatsuya Haga, Muto Yutaka, Yokoyama Shigeyuki: TRNOE studies of methacholine bound to the muscarinic acetylcholine recptor. International Conference on Magnetic Resonance in Biological Systems (ICMRBS), Florence, Italy, August, 2000.
4) Toshiyuki Hamada, Xianglei Yang, Kenneth L. Rinehart, Andrew H.-J. Wang: The Solution Structure of Ecteinascidin 729 - DNA Adduct using NOE-restrained Refinement Procedures. Molecular Biology/Molecular Biophysics Research Symposium, Urbana-Champaign, Illinois, October 31, 1998.
3) Toshiyuki Hamada, Kenneth L. Rinehart: Solution Structure of the Two Conformers of Dehydrodidemnin B determined by NMR spectroscopy. Allerton Conference, Allerton, Illinois, November 8, 1997.
2) 濱田季之・菅原武雄・松永茂樹・伏谷伸宏: Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei. 環太平洋国際会議, ホノルル, 1995 年12月.
1) 濱田季之・楠見武徳・柿澤寛: Absolute Configurations of Some Marine terpeness. American Chemical Society, San Francisco, 1992 年4月.

3.国内学会発表   (作成中)

12) 小瀬 日奈子、須藤 正幸、谷 文都、鬼束 聡明、岡村 浩昭、濵田 季之“ホーリーバジル(Ocimum tenuiflorum)由来のSARS CoV-2メインプロテアーゼ阻害活性物質の単離・構造決定”第67回香料・テルペンおよび精油化学に関する討論会、2023年10月

11) 中村龍之介、松山 紘士、有馬 直道、谷 文都、須藤 正幸、鬼束 聡明、岡村 浩昭、岩川哲夫、濵田 季之“沖縄産ジャノメアメフラシ由来の二次代謝産物の化学構造と生物活性”第67回香料・テルペンおよび精油化学に関する討論会、2023年10月

10) 中村龍之介、松山 紘士、有馬 直道、谷 文都、鬼束 聡明、岡村 浩昭、濵田 季之“沖縄産ジャノメアメフラシ由来の二次代謝産物の単離・構造決定”第60回化学関連支部合同九州大会、2023年7月

9) 永濵佑成、河野未亜、濵田 季之、岡村 浩昭、鬼束 聡明“キラルリン酸誘導体をキラルレセプターに用いたアミン類の光学分割”第60回化学関連支部合同九州大会、2023年7月

8) 松田萌花、濵田 季之、岡村 浩昭、鬼束 聡明“Cerasus jamasakura 抽出物を用いた金属ナノ粒子の合成および機能性評価”第60回化学関連支部合同九州大会、2023年7月

7) 松山 紘士、井上 智恵、室賀 智毅、有馬 直道、土江 松美、谷 文都、鬼束 聡明、岡村 浩昭、濵田 季之“沖縄産ジャノメアメフラシ(Aplysia dactylomela)由来の新規ハロゲン化C15アセトゲニン” 第66回香料・テルペンおよび精油化学に関する討論会、2022年11月

6) 濵田季之、松山紘士“ジャノメアメフラシ由来の新規C15アセトゲニン類やセスキテルペン類の構造と生物活性” 第34回海洋生物活性談話会、2022年10月

5) 濵田 季之“鹿児島発天然物化学研究〜鹿児島の難病治療薬や自然現象の鍵物質の探索研究〜” 鹿児島大学「世界自然遺産候補地・奄美群島におけるグローカル教育研究拠点形成」プログラム公開シンポジウム、2022年3月

4) 濵田 季之“The search of the new marine natural products for development of the therapeutic drug against adult T-cell leukemia”MARINE ECOSYSTEM、2021年11月

3) CHOI DAYEON 、小林 和史、鶴丸 広樹、松山 紘士、谷 文都、鬼束 聡明、岡村 浩昭、濵田 季之“紅藻ハナヤナギ(Chondria armata)由来のブロモトリテルペノイドの構造と抗ATL活性” 第65回香料・テルペンおよび精油化学に関する討論会、2021年10月

2) 田中 倫明、永濵 佑成、御領原 孝尚、濵田 季之、岡村 浩昭、鬼束 聡明“キラルリン酸誘導体を用いたホスト-ゲスト相互作用によるアミノ酸の光学分割法の開発”第11回CSJ化学フェスタ2021、2021年10月

1) 本庄 令奈、濵田 季之、鬼束 聡明、岡村 浩昭、“3-ヒドロキシ-2-ピリドンのDiels-Alder反応における塩基触媒の最適化”第58回化学関連支部合同九州大会、2021年7月

4.その他出版物

Hiroyasu Furukawa, Toshiyuki Hamada, Hiroshi Hirota, Masaji Ishiguro, Tatsuya Haga G Protein-Coupled Receptors: Structure, Function, and Ligand Screening, Taylor & Francis CRC Press・Part III (July, 2005)

5.外部資金(非公開有り)   (作成中)

  • 成人T細胞白血病治療薬を目指した新規天然有機化合物の探索と生物学的特性の解析(平成30-令和2年度; 基盤C)
  • 天然物由来のシガテラ解毒物資の単離、構造決定および作用機序の解明(平成24-26年度; 基盤C)
  • 南方系薬用植物に含まれるシガテラ毒解毒活性物質の構造と機能に関する研究(平成21-23年度; 基盤C)
  • 海綿由来のイオンチャンネル、ポリセオナミドBの立体構造と機能(平成18-20年度; 基盤C)
  • 海綿由来の細胞毒性物質onnamide Aの作用機序に関する研究(平成14-15年度; 若手研究B)