48) K. Matsuyama, T. Inoue, T. Muroga, N. Arima, M. Doe, F. Tani, Y. Ookawa, Y. Okamoto, S. Onitsuka, H. Okamura, T. Iwagawa, T. Hamada. New halogenated C15 acetogenins from Okinawan sea hare
Aplysia dactylomela, 2022年, Tetrahedron, 132889.
47) S-Y Ng, C-S Phan, T. Ishii, T. Kamada, T. Hamada, C. S. Vairappan. Terpenoids from Marine Soft Coral of the Genus Xenia in 1977 to 2019,2020年,molecules,25巻 5386,DOI:
10.3390/molecules25225386
46) T. Hamada, K. Kobayashi, N. Arima, F. Tani, C. S. Vairappan, S. Onitsuka, H. Okamura. Two cytotoxic squalene-derived polyethers from the Japanese red alga Chondria armata,2020年,Natural
Product Research,DOI: 10.1080/14786419.2020.1777411.
45) T. Hamada, K. Harano, R. Niihara, H. Kitahara, M. Yamamoto, C. S. Vairrapan, F. Tani, S. Onitsuka and H. Okamura. Composition and monthly changes of the volatile constituents in the sour
Hetsuka-daidai citrus peel,2020年,Journal of Oleo Science,69巻 6号,643-648ページ
44) T. Kawahata, K. Kawahara, M. Shimokawa, A. Sakiyama, T. Shiraishi, K. Minami, M. Yamamoto, Y. Shinsato, K. Arima, T. Hamada, and T. Furukawa. Involvement of ribosomal protein L11 expression
in sensitivity of gastric cancer against 5-FU,2020年,ONCOLOGY LETTERS,19巻,2258-2264ページ
43) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada, C. S. Vairrapan. 12-Epi-9-deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral, Xenia sp.,2019年,Natural Product Research,33巻
3号,808-813ページ
42) T. Hamada, Y. Matsumoto, C.-S. Phan, T. Kamada, S. Onitsuka, H. Okamura, T. Iwagawa, N. Arima, F. Tani and C. S. Vairappan. Aaptamine-related Alkaloid from the Marine Sponge Aaptos
aaptos.,2019年,Natural Product Communications,14巻 9号,1-3ページ
41) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada and C. S. Vairappan. Cytotoxic Sesquiterpenoids From Soft Soral Capnella imbricate.,2019年,Natural Product Communications,14巻 6号,1-4ページ
40) S. Onitsuka, T. Hamada, H. Okamura. Preparation of antimicrobial gold and silver nanoparticles from tea leaf extracts.,2019年,Colloids and Surfaces B: Biointerfaces,173巻,242-248ページ
39) C.-S. Phan, T. Kamada, T. Hamada, C. S. Vairappan. Cytotoxic Sesterterpenoids from Bornean Sponge Spongia sp.,2018年,Rec. Nat. Prod.,12巻 6号,頁 643-647ページ
38) C.-S. Phan, T. Kamada, T. Ishii, T. Hamada, C. S. Vairappan. A new guaiane-type sesquiterpenoid from a bornean soft coral, Xenia stellifera,2018年,Natural Product Communications,13巻
1号,15-16ページ
37) T. Kamada, C.-S. Phan, T. Hamada, K. Hatai, C. S. Vairappan. Cytotoxic and antifungal terpenoids from bornean soft coral, Sinularia flexibilis,2018年,Natural Product Communications,13巻
1号,17-19ページ
36) C.-S. Phan, T. Kamada, K. Kobayashi, T. Hamada, C. S. Vairappan.15-deoxy-isoxeniolide-A, new diterpenoid from a bornean soft coral, Xenia sp.,2018年,Natural Product Research,32巻
2号,202-207ページ
35) K. Maeda, T. Hamada, S. Onitsuka, H. Okamura. Total Synthesis of the Claimed Structure of (±)-Hyptinin and Structural Revision of Natural Hyptinin,2017年,Journal of Natural Products,80巻
5号,1446-1449ページ
34) M. I. Mohie, Y. Takenoshita, T. Hamada, S. Onitsuka, J. Kurawaki, and H. Okamura. Spontaneous Preparation of Highly Stable Gold Nanoparticle Stabilized with ω-Sulfonylated
alkylsulfanylaniline,2017年,Journal of Oleo Science,66巻 12号,1349-1354ページ
33) T. Hamada, M. Hayasaki, H. Kitahara, K. Yamashita, A. Kariyazaki, S. Onitsuka, H. Okamura. Essential oil composition of citrus peels in Kikai-jima Island, Japan,2017年,American Journal of
Essential Oils and Natural Products,5巻,12-15ページ
32) T. Hamada, D. Harada, M. Hirata, K. Yamashita, K. Palaniveloo, H. Okamura, T. Iwagawa, N. Arima, T. Iriguchi, N. J. de Voogd and C. S. Vairappan. Manoalide-related Sesterterpene from the
Marine Sponge Luffariella variabilis,2015年,Natural Product Communications,10巻,863-864ページ
31) R. Ohira, T. Hamada, S. Onitsuka, and H. Okamura. Base-catalyzed Asymmetric Diels-Alder Reaction of N-Nosyl-3-hydroxy-2-pyridone with a Chiral Acrylate, and Its Application to the Synthesis
of Aminocarbasugars,2015年,Global Science and Technology Forum JChem,2巻,16-20ページ
30) Y. Koyanagi, T. Hamada, T. Iwagawa, and H. Okamura. Asymmetric Synthesis of Ampelomin A and ent-Epiampelomin A, 2015年,Journal of Oleo Science,64巻,449-454ページ
29) T. Hamada, Y. White, M. Nakashima, Y. Oiso, M. Fujita, H. Okamura, T. Iwagawa, N. Arima. The bioassay-guided isolation of growth inhibitors of adult T-cell leukemia (ATL), from the Jamaican
plant Hyptis verticillata, and NMR characterization of hyptoside, 2012年,Molecules,17巻,9931-9938ページ
28) 岡村 浩昭, 岩川 哲夫, 濱田 季之. ジエンの活性化を基盤とする触媒的Diels-Alder反応の開発と生理活性シクロヘキセンオキシド類およびカルバ糖類合成への応用, 2012年 ,有機合成化学協会誌,70巻 ,3号 ,227-239ページ
27) H. Okamura, F. Urabe, T. Hamada, and T. Iwagawa. Base-Catalyzed Asymmetric Diels-Alder Reaction of 3-Hydroxy-2-pyrone and Simple Aryl Vinyl Sulfoxide: Asymmetric Synthesis of
Carbaketopyranoses, 2012年,Bull. Chem. Soc. Jpn. ,85巻,631-633ページ
26) Y. White, T. Hamada, M. Yoshimitsu, M. Nakashima, M.Hachiman, T. Kozako, K. Matsushita, K. Uozumi, S. Suzuki, H. Kofune, T. Furukawa, N. Arima. Novel cytotoxic isolated from Jamaican Hyptis
verticillata jacq induces apoptosis and overcomes multidrug resistance,2011年,Anticancer Research,31巻,4251-4258ページ
25) N. T. Kipassa, H. Okamura, T. Hamada, Y. Morimoto, M. Doe, T. Iwagawa, M. Nakatani. Rings D-seco and B,D-seco tetranortriterpenoids from root bark of Entandrophragma angolense,
2011年,Phytochemistry,72巻,1854-1858ページ
24) T. Iwagawa, T. Kusatsu, K. Tsuha, T. Hamada, H. Okamura, T. Furukawa, S. Akiyama, M. Doe, Y. Morimoto, F. Iwase, K. Takemura. Cytotoxic eunicellin-type diterpenes from the soft coral
Liophyton viscudium, 2011年,Heterocycles,83巻, 2149-2155ページ
23) 濱田 季之. 最大の天然物 ポリセオナミドの構造決定, 2011年, 化学と生物, 49巻 11号, 755-761ページ
22) H. Okamura, J. Kurawaki, T. Iwagawa, T. Hamada, M. Kawashima. One-step Preparation of Gold Nanoparticles Using 4-Acylamindothiophenol as a Reductive Stabilizer, 2010年, Chem. Lett., 12巻,
1258-1260ページ
21) T. Hamada, S. Matsunaga, M. Fujiwara, K. Fujita, H. Hirota, R. Schmucki, P. Guentert, N. Fusetani. Solution structure of polytheonamide B, a highly cytotoxic nonribosomal polypeptide from
marine sponge, 2010年, J. Am. Chem. Soc., 132巻, 12941 - 12945 ページ
20) M. Hirashima, K. Tsuda, T. Hamada, H. Okamura, T. Furukawa, S. Akiyama, Y. Tajitsu, R. Ikeda, M. Komatsu, M. Doe, Y. Morimoto, M. Shiro, R. W. M. van Soest, K. Takemura, and T. Iwagawa.
Cytotoxic isomalabaricane derivatives and a monocyclic triterpene glycoside from the sponge Rhabdastrella globostellata. 2010年, J. Nat. Prod., 73巻, 1512-1518ページ
19) H. Okamura, H. Iiji, T. Hamada, T. Iwagawa, T. Furuno. Diels-Alder reaction of a-tropolone and electron-deficient dienophiles prompted by Et3 or silica gel: a new synthetic method of highly
functionalized homobarrelenone derivatives. 2009年, Tetrahedron, 65巻, 10709-10714ページ
18) N. T. Kipassa , H. Okamura, K. Kina, T. Hamada, T. Iwagawa. Efficient short step synthesis of Corey's tamiflu intermediate, 2008年, Organic Lett., 10巻, 815-816ページ
17) T. Ueki, K. Shintaku, Y. Yonekawa, N. Takatsu, H. Yamada, T. Hamada, H. Hiroshi, and H. Michibata Identification of Vanabin-interacting protein 1 (VIP1) from blood cells of the vanadium-rich
ascidian Ascidia sydneiensis samea, 2007年, Biochimica et Biophysica Acta - General Subjects, 1770巻, 951-957 ページ
16) K. Takada, T. Hamada, H. Hirota, Y. Nakao, S. Matsunaga, R. W. M. van Soest, and N. Fusetani Asteropine A, a Sialidase-Inhibiting Conotoxin-like Peptide from the Marine Sponge Asteropus
simplex, 2006年, Chemistry & Biology, 13巻, 569-574 ページ
15) T. Hamada , Y. Ito, T. Abe, F. Hayashi, P. Guentert, M. Inoue, T. Kigawa, T. Terada, M. Shirouzu, M. Yoshida, A. Tanaka, S. Sugano, S. Yokoyama, and H. Hirota Solution structure of the
antifreeze-like domain of human sialic acid synthase, 2006年, Protein Sci., 15巻, 1010-1016 ページ
14) K. Warabi, T. Hamada, Y. Nakao, S. Matsunaga, H. Hirota, R. W. M. van Soest, and N. Fusetani Axinelloside A, an Unprecedented Highly Sulfated Lipopolysaccharide Inhibiting Telomerase, from
the Marine Sponge, Axinella infundibula, 2005年, J. Am. Chem. Soc., 127巻, 13262 - 13270 ページ
13) T. Hamada, M. Asanuma, T. Ueki, F. Hayashi, N. Kobayashi, S. Yokoyama, H. Michibata, and H. Hirota Solution Structure of Vanabin2, a Vanadium(IV)-Binding Protein from the Vanadium-Rich
Ascidian Ascidia sydneiensis samea, 2005年, J. Am. Chem. Soc., 127巻, 4216 - 4222 ページ
12) T. Hamada, S. Matsunaga, G. Yano, and N. Fusetani Polytheonamides A and B, Highly Cytotoxic Linear Polypeptides of Unprecedented Structural Features, from the Marine Sponge Theonella
swinhoei, 2005年, J. Am. Chem. Soc., 127巻, 110 - 118 ページ
11) T. Hamada, H. Hirota, S. Yokoyama, M. Yamaguchi, N. Otsubo, H. Ishida, M. Kiso, A. Kanamori, and R. Kannagi NMR structure elucidation of cyclic sialyl 6-sulfo Lewis x, a biologically dormant
form of L-selectin ligand. 2003年, Tetrahedron Lett., 44巻, 1167 - 1170 ページ
10) T. Hamada, H. Hirota, S. Yokoyama, N. Otsubo, H. Ishida, M. Kiso, A. Kanamori, and R. Kannagi NMR analysis of novel ganglioside GM4 analogues containing de-N-acetyl and lactamized sialic
acid: probes for searching new ligand structures for human L-selectin, 2002年, Magn. Reson. Chem., 40巻, 517 - 523 ページ
9) S. Tsukamoto, K. Tomise, K. Miyakawa, B-C. Cha, T Abe, T. Hamada, H. Hirota, and T. Ohta CYP3A4 inhibitory activity of new bisalkaloids, dipiperamides D and E, and cognates from white pepper,
2002年, Bioorg. Med. Chem., 10巻, 2981 - 2985 ページ
8) H. Furukawa, T. Hamada, M. K. Hayashi, T. Haga, Y. Muto, H. Hirota, S. Yokoyama, K. Nagasawa, and M. Ishiguro (H. Furukawa and T. Hamada contributed equally to this work.) Conformation of
ligands bound to the muscarinic acetylcholine receptor, 2002年, Mol. Pharmacol, 62巻, 778 - 787 ページ
7) H. Furukawa, T. Haga, Y. Muto, S. Yokoyama, T. Hamada, and H. Hirota Conformation of (S)-methacholine bound to the M2 muscarinic acetylcholine receptor, 2001年, Life Sci., 68巻, 22 - 23
ページ
6) T. Hamada, T. Sugawara, S. Matsunaga, and N. Fusetani Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei, 2. Structure Elucidation, 1994年,
Tetrahedron Lett., 35巻, 609 - 612 ページ
5) T. Hamada, T. Sugawara, S. Matsunaga, and N. Fusetani Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei, 1. Isolation and Component Amino
Acids, 1994年, Tetrahedron Lett., 35巻, 719 - 720 ページ
4) T. Kusumi, T. Hamada, M. Hara, M. O. Ishitsuka, H. Ginda, and H. Kakisawa Structure and Absolute Configuration of Isoclavukerin A, a Component from an Okinawan Soft Coral of Clavularia
species, 1992年, Tetrahedron Lett., 33巻, 2019 - 2022 ページ
3) T. Hamada, T. Kusumi, M. O. Ishitsuka, and H. Kakisawa Strucutre and Absolute Configurations of New Lobane Diterpenoids from the Okinawan Soft Coral Sinularia flexibilis, a Marine Diterpene,
by a Modified Mosher Method, 1992年, Chem. Lett., 33 - 36 ページ
2) T. Kusumi, T. Hamada, M. O. Ishitsuka, I. Otani, and H. Kakisawa Elucidation of the Relative and Absolute Stereochemistry of Lobatriene, a Marine Diterpene, by a Modified Mosher Method, 1992年,
J. Org. Chem., 57巻, 1033 - 1035 ページ
1) T. Iwagawa, T. Hamada, S. Kuroki, and T. Hase Iridoids from Catalpa bignonioides, 1991年, Phytochemistry, 30巻, 4057 - 4060 ページ
21) Toshiyuki Hamada, Kazushi Kobayashi, Naomichi Arima, Fumito Tani, Charles Santhanaraju Vairappan, Yuka Motoi, Satoaki Onitsuka and Hiroaki Okamura“Squalene-derived polyethers, inhibiting
Adult T-cell Leukemia cell, isolated from the red alga, Chondria armata.” 第23回国際海藻学会(23rd International Seaweed Symposium)(口頭発表)2019年4月30日、韓国、済州市
20) Kaoru Warabi, Toshiyuki Hamada, Shigeki Matsunaga, Hiroshi Hirota, Rob W. M. van Soest, Nobuhiro Fusetani: Axinelloside A, a telomerase-inhibitory highly sulfated lipopolysaccharide from the
marine sponge, Axinella infundibula. The 2005 International Chemical Congress of Pacific Basin Societies・Honoruru, Hawaii, USA・December, 2005.
19) Yoko Ito, Toshiyuki Hamada, Takamasa Abe, Fumiaki Hayashi, Peter Guntert, Makoto Inoue, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Mayumi Yoshida, Akiko Tanaka, Sumio Sugano, Shigeyuki
Yokoyama, Hiroshi Hirota Structural and functional analyses of the antifreeze-like domain of human sialic acid synthase. The 1st Asia-Pacific NMR Symposium・Yokohama, Japan・November, 2005.
18) Toshiyuki Hamada, Miwako Asanuma, Tatsuya Ueki, Fumiaki Hayashi, Naohiro Kobayashi, Shigeyuki Yokoyama, Hitoshi Michibata, Hiroshi Hirota Solution structure of vanadium-binding protein,
Vanabin2, from a vanadium-rich ascidian, Ascidia sydneiensis samea, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Hyderabad, India・January, 2005.
17) Toshiyuki Hamada, Miwako Asanuma, Tatsuya Ueki, Hitoshi Michibata, Hiroshi Hirota Solution structure of Vanabin2, a vanadium-binding protein in a vanadium-rich ascidian, Ascidia sydneiensis
samea, International Symposium on Marine Natural Products・Sorrento, Italy・September, 2004.
16) Kentaro Takada, Yoichi Nakao, Toshiyuki Hamada, Hiroshi Hirota, Shigeki Matsunaga, Nobuhiro Fusetani Structure of a neuraminidase inhibitor from the marine sponge Asteropus simplex, Marine
Biotechnology Conference 2003・Chiba, Japan・September, 2003
15) Mizue Yamazaki, Yoshihiro Suzuki, Toshiyuki Hamada, Hiroshi Hirota Chemical cues on metamorphosis in ascidians, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
14) Hiroshi Hirota, Reiko Ban, Toshiyuki Hamada, Seketsu Fukuzawa, Shigeki Matsunaga, Nobuhiro Fusetani Mode of action of onnamide A, a cytotoxic compound from the marine sponge Theonella
swinhoei, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
13) Toshiyuki Hamada, Shigeki Matsunaga, Masako Fujiwara, Kenichi Fujita, Hiroshi Hirota, Nobuhiro Fusetani Three dimensional structure of polytheonamide B, a potent cytotoxic polypeptide from
the marine sponge Theonella swinhoei, Marine Biotechnology Conference 2003・Chiba, Japan・September, 2003.
12) Toshiyuki Hamada, Hiroshi Hirota, Akiko Kanamori, Reiji Kannagi, Nobumasa Otsubo, Hideharu Ishida, Makoto Kiso, Shigeyuki Yokoyama NMR Analysis of Cyclic Sialyl 6-Sulfo Lewis X; Structure
Elucidation and Selectin Binding Activity, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Tronto, Canada・August, 2002.
11) Takamasa Abe, Toshiyuki Hamada, Wataru Kagawa, Hitoshi Kurumizaka, Takehiko Shibata, Shigeyuki Yokoyama, Hiroshi Hirota Conformation Analysis of Single-Stranded DNA Bound to Human Rad52 by
TRNOE Experiments, International Conference on Magnetic Resonance in Biological Systems (ICMRBS)・Tronto, Canada・August, 2002.
10) Takamasa Abe, Toshiyuki Hamada, Wataru Kagawa, Hitoshi Kurumizaka, Takehiko Shibata, Hiroshi Hirota, Shigeyuki Yokoyama Transferred NOE studies of single-starnded DNA bound to the DNA repair
protein HsRad52, Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
9) Reiko Ban, Wakana Saikawa, Shinichi Nishimura, Mizue Yamazaki, Wakana Ohashi, Seketsu Fukuzawa, Toshiyuki Hamada, Hiroshi Hirota Toward the discovery of the target proteins of bioactive
compounds, Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
8) Toshiyuki Hamada, Hiroshi Hirota, Hiroyasu Furukawa, Yutaka Muto, Shigeyuki Yokoyama, Tatsuya Haga Conformational analysis of ligands bound to the muscarinic acetylcholine receptor by TR-NOE,
Canada-UK-Japan Joint Symp. on Toward Post DNA-Sequencing Era・Yokohama, Japan・February, 2002.
7) Hiroshi Hirota, Seketsu Fukuzawa, Toshiyuki Hamada, Reiko Ban, Takashi Kunishima, and Chie Kawabata: Research on mode of action of marine natural products I. Chemical modification of bioactive
compounds from marine sponges. 10th International Symposium on Marine Natural Products, Okinawa, June, 2001.
6) Toshiyuki Hamada, Seketsu Fukuzawa, Miwako Asanuma, Mizue Yamazaki, Reiko Ban, Shigeyuki Yokoyama, and Hirota Hiroshi: Research on mode of action of marine natural products II. Molecular
interaction analysis of bioactive compounds. 10th International Symposium on Marine Natural Products, Okinawa, June, 2001.
5) Toshiyuki Hamada, Hirota Hiroshi, Furukawa hiroyasu, Tatsuya Haga, Muto Yutaka, Yokoyama Shigeyuki: TRNOE studies of methacholine bound to the muscarinic acetylcholine recptor. International
Conference on Magnetic Resonance in Biological Systems (ICMRBS), Florence, Italy, August, 2000.
4) Toshiyuki Hamada, Xianglei Yang, Kenneth L. Rinehart, Andrew H.-J. Wang: The Solution Structure of Ecteinascidin 729 - DNA Adduct using NOE-restrained Refinement Procedures. Molecular
Biology/Molecular Biophysics Research Symposium, Urbana-Champaign, Illinois, October 31, 1998.
3) Toshiyuki Hamada, Kenneth L. Rinehart: Solution Structure of the Two Conformers of Dehydrodidemnin B determined by NMR spectroscopy. Allerton Conference, Allerton, Illinois, November 8,
1997.
2) 濱田季之・菅原武雄・松永茂樹・伏谷伸宏: Polytheonamides, Unprecedented Highly Cytotoxic Polypeptides from the Marine Sponge Theonella swinhoei. 環太平洋国際会議, ホノルル, 1995 年12月.
1) 濱田季之・楠見武徳・柿澤寛: Absolute Configurations of Some Marine terpeness. American Chemical Society, San Francisco, 1992 年4月.